House and the team take on the case of Nick, a book editor who loses his inhibitions. The team realizes Nick has frontal lobe inhibition, which causes him to speak his mind having no control over what

A patient with both male and female DNA has the team stumped. Meanwhile, House starts acting nicely, raising Cuddy’s and Wilson’s suspicions that something is terribly wrong.

House struggles with his own beliefs as he takes on a case of priest with a disturbing past who runs a shelter for homeless people and sees a vision of Jesus.

A former cancer researcher collapses in the middle of a cooking class, and the team are forced to reevaluate their own lives when they learn she gave up a promising career to seek personal happiness.

The team take on the case of a Special Education teacher who spits up blood and collapses in the middle of class. Meanwhile, Cameron finds herself taking on some of Cuddy’s duties, including dealing with House, and Foreman has to make a decision concerning Thirteen’s participation in the clinic trials.

Thirteen receives treatment by Foreman while taking part in his clinical trial on Huntington’s Disease.

House and his team deal with a bullied girl who collapses during her school’s Christmas program. Meanwhile, Foreman and Thirteen grow closer during the Huntington’s disease drug trials, House gives

The team take on the case of a fitness guru on an all-natural diet who collapsed while filming a video. Meanwhile, Foreman conducts Huntington’s Disease drug trials and Thirteen signs on as a subject

A man takes over Cuddy’s office and holds House, Thirteen, and several patients hostage. His demand? A diagnosis. The man forces Thirteen to act as a guinea pig for his treatments and House has to en

While Foreman takes on a pediatric case on his own, the rest of the team deals with a 16-year-old factory manager and emancipated minor who collapses at work. When Foreman’s patient takes a turn for